Epigenetics is the link between nature – our genetic heritage – and nurture – how we build on this heritage every day. This is particularly true when it comes to aging, as the genetic background is a relatively weak predictor of longevity compared to lifestyle. Aging is a combination of time, inherited genes, environment, and lifestyle, all factors directly impacting on our epigenetic landscape. Recent research has demonstrated that biological age, based on epigenetic markers, is a promising predictor of longevity and deleterious effects of aging such as chronic diseases and cognitive decline. Most importantly, it has been shown that when triggering the right levers, biological age can be reduced, and impaired epigenetics can be reversed.